Transcranial magnetic stimulation and other evoked potentials in pediatric multiple sclerosis [In Process Citation]
Dan B; Christiaens F; Christophe C; Dachy B
Pediatr Neurol 2000 Feb;22(2):136-8 [MEDLINE record in process]

In Children, Multiple Sclerosis Is Rare And Has Some
Clinical And Paraclinical Differences Compared With
Adults. The Assessment Of Corticospinal Motor Tracts
Is Expected To Be Relevant Because Of Their Frequent
Early Involvement In This Disease. Reported Are The
Results Of Transcranial Magnetic Stimulation In Two
Children Who Presented At 12 And 9 Years Of Age With
Clinically Probable And Definite Multiple Sclerosis,
Respectively. In Patient 1 The Excitatory Cortical
Threshold For The Upper Limbs Was Abnormally Raised.
In Patient 2 The Latency Of The Motor-evoked
Potentials Was Considerably Increased For The Right
Tibialis Anterior Muscle, With A Slowing Of The Central
Conduction Time. Although These Abnormalities May
Be Consistent With Central Conduction Impairment,
They May Alternatively Suggest Early Axonal Damage
Because Irreversible Axonal Lesions Occurring At The
Onset Of The Disease Have Recently Been Reported.
Testing Of Central Motor Tracts, In Addition To Visual,
Auditory, And Somatosensory Pathways, Therefore
Appears Appropriate In The Multimodal Assessment Of
Pediatric Patients With Suspected Multiple Sclerosis.
2000/30 09:00




em Psiquiatría